2-Methyl-2-propanyl [(2R)-1-hydroxy-2-propanyl]carbamate(CAS: 106391-86-0)

2-Methyl-2-propanyl [(2R)-1-hydroxy-2-propanyl]carbamate (CAS: 106391-86-0) is a colorless, crystalline solid at room temperature. Its molecular weight is approximately 144.17 g/mol. The compound is slightly soluble in water and has good solubility in organic solvents. It is chemically stable under normal conditions but can react with strong bases and acids. The compound is a primary amide, which can undergo nucleophilic substitution reactions and hydrolysis under certain conditions.

2-Methyl-2-propanyl [(2R)-1-hydroxy-2-propanyl]carbamate can be synthesized via a two-step process. First, 2-methyl-2-propanol is treated with sodium hydride to form the enolate, which then reacts with ethyl carbamate to give the desired product. Alternatively, it can be produced by the nucleophilic addition of 2-methyl-2-propanol to ethyl cyanoacetate followed by hydrolysis. The yield is typically around 70-80%, and the reaction is performed under anhydrous conditions to avoid side reactions.

2-Methyl-2-propanyl [(2R)-1-hydroxy-2-propanyl]carbamate (CAS: 106391-86-0) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also utilized in the production of certain polymers and as a chemical reagent in analytical chemistry. The compound has potential applications in sensors and as a building block for organic synthesis, although its specific use cases in these areas are more specialized.

When handling 2-Methyl-2-propanyl [(2R)-1-hydroxy-2-propanyl]carbamate (CAS: 106391-86-0), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight. Handling should be done in a well-ventilated area or fume hood to minimize inhalation risks. In case of a spill, it should be cleaned up immediately using appropriate absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed guidelines on handling and disposal.