How is 2-Methyl-2-propanyl [(2R)-1-hydroxy-2-propanyl]carbamate (CAS: 106391-86-0) typically synthesized?

2-Methyl-2-propanyl [(2R)-1-hydroxy-2-propanyl]carbamate can be synthesized via a two-step process. First, 2-methyl-2-propanol is treated with sodium hydride to form the enolate, which then reacts with ethyl carbamate to give the desired product. Alternatively, it can be produced by the nucleophilic addition of 2-methyl-2-propanol to ethyl cyanoacetate followed by hydrolysis. The yield is typically around 70-80%, and the reaction is performed under anhydrous conditions to avoid side reactions.