3,5-Bis(trifluoromethyl)benzaldehyde(CAS: 401-95-6)

3,5-Bis(trifluoromethyl)benzaldehyde (CAS: 401-95-6) is a crystalline compound with a molecular weight of approximately 233.12 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetonitrile. It is highly reactive, particularly towards nucleophiles and reducing agents due to the presence of trifluoromethyl groups.

3,5-Bis(trifluoromethyl)benzaldehyde is typically synthesized through a multistep process involving the formation of 3,5-bis(trifluoromethyl)benzyl bromide followed by reductive amination. The reaction often uses palladium-based catalysts and involves high yields and good selectivity.

3,5-Bis(trifluoromethyl)benzaldehyde (CAS: 401-95-6) is used in various industries, including pharmaceuticals for the synthesis of complex organic molecules, and in the polymer industry for making specialized polymers. It also finds applications in the production of sensors and semiconductors.

When handling 3,5-Bis(trifluoromethyl)benzaldehyde (CAS: 401-95-6), it is essential to use personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.