4-Nitrobenzyl 3-oxobutanoate(CAS: 61312-84-3)

4-Nitrobenzyl 3-oxobutanoate is a crystalline compound with a molecular weight of approximately 268.12 g/mol. It has a solubility of about 0.035 g/L in water. The compound is reactive and susceptible to hydrolysis under basic conditions. It is also sensitive to heat and light, leading to decomposition.

4-Nitrobenzyl 3-oxobutanoate is typically synthesized via a multi-step process involving the formation of a nitrobenzyl ester followed by the introduction of a 3-oxobutanoate moiety. Common methods include the reaction of 4-nitrobenzyl chloroformate with 3-oxobutanoic acid in the presence of a catalytic amount of a base, such as triethylamine, with yields of up to 90%.

4-Nitrobenzyl 3-oxobutanoate is used in the pharmaceutical industry for the synthesis of various organic compounds and as a protective group in chemical reactions. It is also utilized in the polymer industry for the modification of polymers and in the semiconductor industry for the development of functional materials and sensors.

When handling 4-Nitrobenzyl 3-oxobutanoate, it is important to use appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.