2-Bromo-4,5-difluorobenzonitrile(CAS: 64695-82-5)

2-Bromo-4,5-difluorobenzonitrile (CAS: 64695-82-5) is a crystalline solid with a molecular weight of approximately 218.02 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetonitrile. The compound is moderately reactive, particularly towards nucleophiles and reducing agents. It is used in synthesis due to its stability and reactivity in organic transformations.

2-Bromo-4,5-difluorobenzonitrile is typically synthesized by the electrophilic aromatic substitution of 4,5-difluorobenzenecarbothioic acid hydrazide with bromine in the presence of base. This method provides good yield and selectivity, making it a common approach in the laboratory and industry.

2-Bromo-4,5-difluorobenzonitrile (CAS: 64695-82-5) is primarily used in the pharmaceutical and polymer industries. It serves as a key intermediate in the synthesis of various drug molecules and also finds applications in the development of new functional polymers with specific properties.

When handling 2-Bromo-4,5-difluorobenzonitrile (CAS: 64695-82-5), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or under a fume hood. In case of spill, immediately clean up with appropriate absorbent materials and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.