N-(4-Nitrophenyl)-L-glutamine(CAS: 7300-59-6)

N-(4-Nitrophenyl)-L-glutamine (CAS: 7300-59-6) is a white to off-white crystalline solid with a molecular weight of approximately 284.14 g/mol. It has limited solubility in water and moderate solubility in organic solvents. The compound exhibits moderate reactivity, particularly in acidic and basic conditions. It is stable under normal storage conditions but should be protected from moisture and light.

N-(4-Nitrophenyl)-L-glutamine can be synthesized through the nitration of phenylalanine with concentrated nitric acid followed by coupling with L-glutamine. The synthesis typically involves the use of a mineral acid as a catalyst and results in a yield of around 70-75%. The process requires careful temperature control and handling due to the reactivity of the intermediate nitro compound.

N-(4-Nitrophenyl)-L-glutamine (CAS: 7300-59-6) finds applications in the pharmaceutical industry for developing new drugs, particularly in research and development of anti-inflammatory and analgesic compounds. It is also used in the synthesis of certain polymers and as a precursor in the production of chemical sensors and semiconductors.

When handling N-(4-Nitrophenyl)-L-glutamine (CAS: 7300-59-6), ensure proper personal protective equipment (PPE) is worn, including gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to minimize exposure. Store in a cool, dry place away from direct sunlight and heat sources. In case of a spill, neutralize with an appropriate reagent and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling instructions.