(~2~H_3_)Methanol(CAS: 1849-29-2)

(~2~H_3_)Methanol, also known as deuterated methanol, has a CAS number of 1849-29-2. It is a colorless liquid with a pungent odor. It has a molecular weight of 33.05 g/mol and a density of 0.786 g/cm³ at 20°C. It is miscible with water and most organic solvents. It is slightly more reactive than regular methanol and can undergo hydrogen exchange reactions with deuterium. It is used in spectroscopy, as a solvent, and in the synthesis of other organic compounds.

(~2~H_3_)Methanol is typically synthesized by the deuterium exchange of methanol with heavy water (D₂O) in the presence of a strong acid catalyst such as boron trifluoride or hydrochloric acid. The reaction is carried out at room temperature and the yield is around 80-90%. The selectivity for deuterium exchange is high, making (~2~H_3_)Methanol a pure product.

(~2~H_3_)Methanol is used in various industries such as pharmaceuticals, where it serves as a solvent for reactions and as a precursor for the synthesis of other compounds. It is also used in the polymer industry as a solvent and in the production of deuterated solvents for NMR spectroscopy. Additionally, it is used in the semiconductor industry as a cleaning agent and in the production of deuterated solvents for chemical analysis.

When handling (~2~H_3_)Methanol, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and sources of ignition. In case of spill, it should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. For detailed safety information, refer to the Material Safety Data Sheet (MSDS/SDS).