1-Ethyl-6-fluoro-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid(CAS: 70458-92-3)

1-Ethyl-6-fluoro-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid is a crystalline compound with a molecular weight of approximately 328.31 g/mol. It has a low solubility in water (0.012 g/100 mL at 25°C) but is soluble in organic solvents like DMSO and acetonitrile. The compound exhibits good stability under normal conditions but reacts with strong bases and acids. It can be identified by its UV/Vis spectrum and NMR spectroscopy.

The compound is typically synthesized via a multi-step process involving the reaction of a fluoroquinoline with a piperazine derivative. Key steps include the formation of an intermediate quinoline ring and subsequent reactions to introduce the ethyl and methyl groups. The synthesis often employs catalytic hydrogenation and selective alkylation reactions. The overall yield is moderate, around 50-60%, and the process requires careful control of reaction conditions to achieve high purity.

1-Ethyl-6-fluoro-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It finds applications in the development of novel therapeutic agents, particularly in areas such as neurology and immunology. Additionally, it has potential uses in polymer science and as a component in sensor technology due to its unique chemical properties.

When handling 1-Ethyl-6-fluoro-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be carried out in a well-ventilated fume hood to minimize exposure. Spills should be cleaned up immediately with appropriate absorbent materials. Refer to the safety data sheet (SDS) for specific handling and storage instructions to ensure compliance with laboratory safety standards.