5-Bromo-1-indanone(CAS: 34598-49-7)

5-Bromo-1-indanone is a crystalline compound with a molecular weight of approximately 225.03 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and chloroform. Chemically, it is reactive towards nucleophiles, making it useful in various synthetic transformations. It has a melting point of about 85-87°C and is known for its stability under room temperature conditions.

5-Bromo-1-indanone is commonly synthesized via the bromination of 1-indanone. This process often involves using bromine in the presence of a Lewis acid catalyst, such as aluminum bromide. The reaction typically provides a yield of around 80-85%, with good selectivity towards the brominated product.

5-Bromo-1-indanone is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also has applications in the polymer industry for modifying polymer properties. Additionally, it is used in the development of sensors and semiconductors due to its unique chemical reactivity and stability.

Proper handling of 5-Bromo-1-indanone requires the use of personal protective equipment (PPE) such as gloves, goggles, and lab coats. It should be stored in a cool, dry place away from direct sunlight and flammable materials. In case of a spill, it should be cleaned up using appropriate absorbents and disposed of in accordance with local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.