3-[(E)-Octadec-1-enyl]oxolane-2,5-dione(CAS: 28777-98-2)

3-[(E)-Octadec-1-enyl]oxolane-2,5-dione is a white to light yellow crystalline solid. The molecular weight is approximately 326.48 g/mol. It is slightly soluble in water but soluble in common organic solvents like ethanol and acetone. Chemically, it is relatively stable but can react with strong bases and reducing agents. It has a pKa of around 7.5 and a melting point of 75-77°C.

3-[(E)-Octadec-1-enyl]oxolane-2,5-dione can be synthesized via a Wittig reaction involving methyl oxalate and 1-octadecene. The reaction is catalyzed by phosphorus ylide and proceeds under mild conditions. The yield is typically around 75%, and the product is purified by column chromatography using silica gel as the stationary phase.

3-[(E)-Octadec-1-enyl]oxolane-2,5-dione finds applications in the pharmaceutical industry as an intermediate for drug synthesis. It is also used in the polymer industry to enhance the performance of certain polymers and in the sensor industry for developing gas sensors. Additionally, it has potential uses in the semiconductor industry for certain chemical processes.

When handling 3-[(E)-Octadec-1-enyl]oxolane-2,5-dione, it is important to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be handled carefully and neutralized with an appropriate solution. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.