1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-Echinocandin B Hydrochloride(CAS: 1029890-89-8)

1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-Echinocandin B Hydrochloride is a crystalline compound with a molecular weight of approximately 1027.14 g/mol. It has a solubility of 0.1 g/100 mL in water and is slightly soluble in organic solvents. This compound is moderately reactive with bases and acidic conditions. It is stable under normal storage conditions but should be protected from moisture and light.

1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-Echinocandin B Hydrochloride is synthesized through a multi-step process involving the condensation of ornithine derivatives with echinocandin intermediates. The synthesis typically uses catalytic amounts of a Lewis acid, such as titanium(IV) isopropoxide, and achieves a yield of around 70%. The reaction is highly selective and proceeds with good regioselectivity.

1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-Echinocandin B Hydrochloride is primarily used in the pharmaceutical industry for the development of antifungal drugs. It also finds applications in the research of new antifungal agents and as a reference compound in academic studies. Its unique chemical properties make it a valuable reagent in the study of carbohydrate chemistry and molecular biology.

When handling 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-Echinocandin B Hydrochloride, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work must be conducted in a well-ventilated area or a fume hood to avoid inhalation of the compound. Spills should be handled with caution using absorbent materials and a spill kit. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.