N,N,N-Trimethylmethanaminium acetate(CAS: 10581-12-1)

N,N,N-Trimethylmethanaminium acetate (CAS: 10581-12-1) is a white crystalline solid with a molecular weight of approximately 168.22 g/mol. It has a pKa of 10.7 and is moderately soluble in water. The compound is reactive towards basic substances and can undergo hydrolysis under acidic conditions. It is miscible with ethanol and other organic solvents.

N,N,N-Trimethylmethanaminium acetate can be synthesized by reacting methylamine with acetic anhydride in the presence of a catalytic amount of a strong acid like hydrochloric acid or sulfuric acid. The reaction involves the formation of methyl acetate followed by the protonation of the amine group to form the salt.

N,N,N-Trimethylmethanaminium acetate (CAS: 10581-12-1) is primarily used in the pharmaceutical industry for its buffering and stabilizing properties, particularly in the formulation of pH-sensitive drugs. It is also utilized in polymer science for its role as a coupling agent and in the production of sensors and semiconductors.

When handling N,N,N-Trimethylmethanaminium acetate (CAS: 10581-12-1), it is essential to wear appropriate personal protective equipment (PPE) including gloves and safety goggles. The compound should be stored in a cool, dry place away from acids and bases. In case of spillage, immediately clean up using appropriate procedures and consult the Safety Data Sheet (SDS) for further guidance.