2-Pyridinecarboxylic acid 1-oxide(CAS: 824-40-8)

2-Pyridinecarboxylic acid 1-oxide (CAS: 824-40-8) is a crystalline solid with a molecular weight of approximately 130.12 g/mol. It has a melting point of 220-222°C and a solubility of 0.25 g/100 mL in water at 25°C. The compound is moderately reactive, particularly towards bases and reducing agents. It is used in organic synthesis and as a reagent in various laboratory applications.

2-Pyridinecarboxylic acid 1-oxide (CAS: 824-40-8) can be synthesized by the oxidation of 2-pyridinecarboxylic acid using appropriate oxidizing agents such as pyridinium chlorochromate (PCC) or potassium permanganate. The reaction is carried out in an anhydrous medium and typically provides good yields. Care should be taken to ensure proper mixing and temperature control during the reaction.

2-Pyridinecarboxylic acid 1-oxide (CAS: 824-40-8) is used in various industries, including pharmaceuticals, where it serves as a precursor in the synthesis of certain drugs. It is also used in the production of polymers, sensors, and semiconductors. Its ability to participate in various chemical reactions makes it a valuable reagent in organic chemistry and materials science.

When handling 2-Pyridinecarboxylic acid 1-oxide (CAS: 824-40-8), appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat should be worn. This compound should be handled in a well-ventilated area or a fume hood to minimize exposure to vapors. Spills should be cleaned up carefully according to safety data sheet (SDS) guidelines. Always refer to the SDS for specific safety information and emergency procedures.