6-Chloro-5-(2-chloroethyl)-1,3-dihydro-2H-indol-2-one(CAS: 118289-55-7)

6-Chloro-5-(2-chloroethyl)-1,3-dihydro-2H-indol-2-one (CAS: 118289-55-7) is a crystalline solid with a molecular weight of approximately 295.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. The compound exhibits moderate reactivity, particularly towards nucleophilic substitution reactions. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

6-Chloro-5-(2-chloroethyl)-1,3-dihydro-2H-indol-2-one (CAS: 118289-55-7) is typically synthesized via the condensation of 2-chloroethylamine with indole-3-carbaldehyde. This reaction can be catalyzed by Lewis acids like aluminum chloride, with good yield and high selectivity. The product is purified by recrystallization from organic solvents.

6-Chloro-5-(2-chloroethyl)-1,3-dihydro-2H-indol-2-one (CAS: 118289-55-7) finds applications in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It may also be used in the polymer industry for the development of new materials and in the sensor industry for its ability to interact with specific chemical species.

When handling 6-Chloro-5-(2-chloroethyl)-1,3-dihydro-2H-indol-2-one (CAS: 118289-55-7), it is crucial to wear appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place with good ventilation. In case of spill, it should be contained and disposed of according to safety data sheet (SDS) guidelines. Always work in a fume hood to avoid inhalation risk.