(5E)-Rosiglitazone(CAS: 122320-74-5)

(5E)-Rosiglitazone, with CAS number 122320-74-5, is a thiazolidinedione antidiabetic drug. It is used to treat type 2 diabetes mellitus. Chemically, it is a derivative of rosiglitazone with a 5E configuration. It exhibits insulin-sensitizing properties by activating peroxisome proliferator-activated receptor gamma (PPAR-γ).

(5E)-Rosiglitazone is primarily used to manage type 2 diabetes mellitus. It is an antidiabetic drug that improves glucose metabolism by enhancing insulin sensitivity in adipose tissue, liver, and muscle. This compound is employed in oral formulations for long-term treatment of diabetes.

(5E)-Rosiglitazone is generally considered safe when used under medical supervision. However, it can cause side effects such as weight gain, fluid retention, and an increased risk of cardiovascular events. Patients should follow medical advice and regular monitoring to manage potential risks.

(5E)-Rosiglitazone should be stored at room temperature (15°C to 30°C) and protected from light. It should be kept in a tightly closed container to prevent moisture and degradation. Avoid exposure to extreme temperatures and keep out of reach of children and pets.