5-Amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile(CAS: 330792-70-6)

5-Amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile is a crystalline solid with a molecular weight of approximately 314.31 g/mol. It is slightly soluble in water but soluble in common organic solvents like DMSO, DMF, and acetonitrile. This compound is known for its stable structure and low reactivity under normal conditions. However, it can react with strong bases and acids to form different products.

5-Amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile is typically synthesized via a multi-step process involving the protection of the phenolic hydroxyl group, followed by coupling with the appropriate pyrazole derivative. The final step involves deprotection and purification. This synthesis typically requires the use of catalysts and reagents such as triphenylphosphine and HATU for the coupling reaction.

5-Amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile is used in various industries, including pharmaceuticals, where it serves as a potential lead compound for drug development. It also has applications in the formulation of sensors and semiconductors due to its unique chemical properties.

When handling 5-Amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and laboratory coat. Work should be conducted in a well-ventilated fume hood to minimize inhalation risks. In case of spill, use absorbent material to contain the spill and dispose of it according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.