1-[4-(Benzyloxy)phenyl]-1-propanone(CAS: 4495-66-3)

The compound 1-[4-(Benzyloxy)phenyl]-1-propanone (CAS: 4495-66-3) is a white crystalline solid with a molecular weight of approximately 262.27 g/mol. It has a low solubility in water (0.1 g/100 ml at 20°C) but is more soluble in organic solvents like ethanol and acetone. It is a stable compound under normal conditions, but it can undergo intramolecular rearrangement under basic conditions. The compound is not reactive towards common oxidizing or reducing reagents. It is used in various chemical reactions due to its functional groups.

1-[4-(Benzyloxy)phenyl]-1-propanone (CAS: 4495-66-3) is typically synthesized via the Corey-Kim benzylization protocol. The reaction involves the coupling of 4-benzyloxybenzaldehyde with acetone in the presence of a catalyst such as Lewis acid or a base. The yield is generally high, and the product can be isolated by recrystallization or column chromatography.

1-[4-(Benzyloxy)phenyl]-1-propanone (CAS: 4495-66-3) is used in the pharmaceutical industry for the synthesis of various drugs due to its functional groups. It is also utilized in the polymer industry for the preparation of high-performance materials. Additionally, it can be used in the production of sensors and semiconductors due to its reactivity and structural properties.

When handling 1-[4-(Benzyloxy)phenyl]-1-propanone (CAS: 4495-66-3), appropriate personal protective equipment (PPE) should be worn, including gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up carefully using appropriate absorbent materials. For detailed safety information, refer to the Safety Data Sheet (SDS) for the compound.