7-Methoxy-4-oxo-1,4-dihydro-6-quinazolinyl acetate(CAS: 179688-53-0)

7-Methoxy-4-oxo-1,4-dihydro-6-quinazolinyl acetate (CAS: 179688-53-0) is a crystalline compound with a molecular weight of approximately 266.24 g/mol. It is slightly soluble in water but more soluble in organic solvents like methanol and ethanol. The compound is known for its reactivity in esterification and acylation reactions. It has a melting point of around 135-137°C and is stable under normal conditions but requires careful handling due to its potential to undergo hydrolysis.

7-Methoxy-4-oxo-1,4-dihydro-6-quinazolinyl acetate is typically synthesized by the acetylation of 7-methoxy-4-oxo-1,4-dihydro-6-quinazoline with acetic anhydride in the presence of a catalytic amount of p-toluenesulfonic acid. The reaction is carried out under reflux conditions leading to high yield and selectivity. The product is usually purified by recrystallization from a suitable solvent.

7-Methoxy-4-oxo-1,4-dihydro-6-quinazolinyl acetate (CAS: 179688-53-0) finds application in the pharmaceutical industry for its potential as an intermediate in drug synthesis. It is also used in the polymer industry as a stabilizer and in the development of sensors and semiconductors for electronic applications.

When handling 7-Methoxy-4-oxo-1,4-dihydro-6-quinazolinyl acetate (CAS: 179688-53-0), it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coats. Ensure the use of a fume hood during preparation and handling to minimize exposure to the vapor. Spills should be cleaned up immediately using absorbent materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.