2-Amino-1-(3-fluorophenyl)ethanone hydrochloride (1:1)(CAS: 93102-97-7)

2-Amino-1-(3-fluorophenyl)ethanone hydrochloride has a crystalline form with a molecular weight of approximately 234.7 g/mol. It is slightly soluble in water and ethanol. The compound exhibits moderate reactivity, especially under basic conditions. It is stable under normal conditions but should be stored in a cool, dry place to prevent degradation.

2-Amino-1-(3-fluorophenyl)ethanone hydrochloride is typically synthesized via a multi-step process involving the reaction of 3-fluorophenylacetic acid with hydroxylamine hydrochloride. The reaction is catalyzed by a strong base such as sodium hydroxide, yielding the target compound with good yield and selectivity. Post-synthesis, the hydrochloride salt is obtained by treating the amine intermediate with hydrochloric acid.

2-Amino-1-(3-fluorophenyl)ethanone hydrochloride is used in the pharmaceutical industry for the synthesis of drugs with specific pharmacological activities. It is also employed in the development of sensors and semiconductors due to its functional groups, which can be utilized in various applications requiring specific reactivity and solubility.

When handling 2-Amino-1-(3-fluorophenyl)ethanone hydrochloride, it is crucial to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure to the compound. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.