1-Chloro-3-phenylacetone(CAS: 937-38-2)

1-Chloro-3-phenylacetone (CAS: 937-38-2) is a white or pale yellow crystalline solid. Its molecular weight is approximately 226.68 g/mol. This compound is slightly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is moderately reactive and can undergo nucleophilic substitution reactions. It is also prone to hydrolysis under basic conditions.

1-Chloro-3-phenylacetone (CAS: 937-38-2) is typically synthesized via the reaction of 3-phenylacetyl chloride with sodium chloride in the presence of an acid catalyst. This process involves the nucleophilic substitution of the chloride ion, leading to the formation of the target compound with high selectivity and yield.

1-Chloro-3-phenylacetone (CAS: 937-38-2) is used in various industries, particularly in pharmaceuticals for the synthesis of certain drugs, and in the production of fragrances and flavorings. It is also utilized in the formulation of certain chemical sensors and as a precursor in the synthesis of semiconductors.

When handling 1-Chloro-3-phenylacetone (CAS: 937-38-2), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Proper waste disposal protocols should be followed, and spills should be cleaned up according to the Material Safety Data Sheet (MSDS).