Ethyl 2-(bromomethyl)benzoate(CAS: 7115-91-5)

Ethyl 2-(bromomethyl)benzoate is a white crystalline solid with a molecular weight of approximately 253.02 g/mol. It is slightly soluble in water but soluble in common organic solvents like ethanol and acetone. The compound is reactive towards nucleophiles and can undergo substitution reactions. It is also prone to hydrolysis under basic conditions.

Ethyl 2-(bromomethyl)benzoate is commonly synthesized via the reaction of ethyl benzoate with bromine in the presence of a Lewis acid catalyst such as aluminum bromide. The reaction involves the substitution of a methyl group on the benzene ring with a bromomethyl group, yielding a high yield of the desired product with good selectivity.

Ethyl 2-(bromomethyl)benzoate finds applications in the pharmaceutical industry as an intermediate in the synthesis of various drug molecules. It is also used in the polymer industry as a monomer or modifier. Additionally, it has potential applications in the sensor and semiconductor industries due to its reactive properties.

Proper handling of Ethyl 2-(bromomethyl)benzoate requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from heat and moisture. In case of spill, it should be handled according to the Safety Data Sheet (SDS) guidelines, which include the use of appropriate absorbents and disposal methods. Always ensure the use of a fume hood when handling the compound to prevent inhalation.