5-Bromo-4-methyl-2-pyrimidinamine(CAS: 17321-93-6)

5-Bromo-4-methyl-2-pyrimidinamine (CAS: 17321-93-6) is a crystalline solid with a molecular weight of approximately 205.02 g/mol. It has a melting point of 160-162°C and is moderately soluble in water and ethanol. This compound shows reactivity towards nucleophilic substitution and condensation reactions.

5-Bromo-4-methyl-2-pyrimidinamine (CAS: 17321-93-6) is typically synthesized via electrophilic aromatic substitution using bromination of 4-methyl-2-pyrimidinamine. The synthesis involves using bromine in the presence of a Lewis acid catalyst such as iron(III) chloride. The yield is around 75-80%, with high selectivity.

5-Bromo-4-methyl-2-pyrimidinamine (CAS: 17321-93-6) finds applications in pharmaceuticals for the synthesis of certain drugs, and in the chemical industry for various reactions and intermediate production. It is also used in the development of sensors and as a precursor in the semiconductor industry.

When handling 5-Bromo-4-methyl-2-pyrimidinamine (CAS: 17321-93-6), wear personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work in a fume hood to minimize exposure. Ensure proper storage in a cool, dry place away from direct sunlight. In case of spills, clean up with appropriate absorbent materials and dispose of according to local waste regulations. Refer to the Material Safety Data Sheet (MSDS) for detailed safety information.