1,2,4-triazolo[4,3-a]pyridin-3-ol(CAS: 71-62-5)

1,2,4-triazolo[4,3-a]pyridin-3-ol (CAS: 71-62-5) is a crystalline solid with a molecular weight of approximately 153.16 g/mol. It has a limited water solubility and is slightly soluble in organic solvents. This compound exhibits moderate reactivity, primarily through its nitrogen-containing functional groups, which can participate in various organic reactions such as nucleophilic substitution and condensation reactions.

1,2,4-triazolo[4,3-a]pyridin-3-ol (CAS: 71-62-5) is commonly synthesized via the condensation of 3-aminopyridine with hydroxytetrazole, followed by deamination. The reaction is typically catalyzed by a strong acid, such as concentrated sulfuric acid, and proceeds with good yield. Selectivity and yield can be influenced by the choice of reagents and reaction conditions.

1,2,4-triazolo[4,3-a]pyridin-3-ol (CAS: 71-62-5) finds applications in various industries. It is used in pharmaceuticals for its biological activity, particularly in the development of new drugs. In addition, it is utilized in the synthesis of novel materials and sensors due to its unique chemical properties, making it a valuable intermediate in chemical and materials science research.

Proper handling of 1,2,4-triazolo[4,3-a]pyridin-3-ol (CAS: 71-62-5) is essential to ensure safety. Wear appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat, when handling the compound. Work in a well-ventilated area or a fume hood to minimize exposure. Store the compound in a cool, dry place away from incompatible materials. In case of a spill, notify your supervisor and follow the appropriate spill cleanup procedures as outlined in the safety data sheet (SDS).