(4aR,6R,7R,7aS)-6-(6-Amino-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide(CAS: 60-92-4)

This compound is a complex organic molecule with the chemical formula C10H14N5O7P. It features a purine ring functionalized with amino and hydroxyl groups, along with a phosphonate structure. Known for its stability in aqueous solutions, it is primarily used in pharmaceutical research as a nucleotide analog. Its unique stereochemistry (4aR,6R,7R,7aS) contributes to its biological activity and specificity.

This compound is primarily utilized in pharmaceutical research for developing antiviral and antitumor agents due to its nucleotide-like structure. It serves as a key intermediate in organic synthesis and is studied for its potential in enzyme inhibition. Additionally, it finds application in biochemical studies to understand purine metabolism and drug-target interactions.

Safety data for this compound is limited, but it is generally considered to have moderate toxicity. Handling requires protective measures such as gloves, goggles, and a fume hood to avoid skin or respiratory exposure. It is not classified as carcinogenic or mutagenic under standard protocols, but proper ventilation and adherence to OSHA guidelines are recommended for safe use in laboratory settings.

Store this compound in a sealed, moisture-proof container at 2-8°C to maintain stability. Protect from light by using amber-colored containers and avoid exposure to air. Due to its hygroscopic nature, it should be kept in a dry environment with desiccants. Long-term storage may require nitrogen atmosphere to prevent degradation.