6-Hydroxy-2-naphthaldehyde(CAS: 78119-82-1)

6-Hydroxy-2-naphthaldehyde is a white crystalline solid with a molecular weight of approximately 168.16 g/mol. It has a slight naphthalene-like odor and is slightly soluble in water. Chemically, it is moderately reactive, showing good reactivity towards electrophiles. It is used as a precursor in organic synthesis and in analytical chemistry due to its functional groups.

6-Hydroxy-2-naphthaldehyde is typically synthesized by reduction of 2-naphthoic aldehyde using a hydrogenation catalyst such as Raney nickel. The reaction involves converting the aldehyde group to a hydroxy group, and this method provides good yields and selectivity. Other methods include hydroxylation of 2-naphthaldehyde, which can also be achieved using metal complexes or oxidizing agents.

6-Hydroxy-2-naphthaldehyde is used in the pharmaceutical industry as a precursor for the synthesis of various drugs, in the polymer industry for modifying polymers, and in the semiconductor industry for use in organic thin-film transistors. It is also utilized in analytical chemistry for reagents and sensors.

When handling 6-Hydroxy-2-naphthaldehyde, ensure proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a cool, dry place away from heat sources. Use a fume hood during handling to avoid inhalation. In case of spill, avoid contact with skin and eyes, and clean up with appropriate chemicals as per safety data sheet (SDS).