2-Methyl-4-nitropyridine(CAS: 13508-96-8)

2-Methyl-4-nitropyridine is a crystalline solid with a molecular weight of approximately 171.08 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. This compound is mildly reactive and can decompose upon exposure to heat or strong reducing agents. It exhibits basic properties due to the presence of the pyridine ring.

2-Methyl-4-nitropyridine is commonly synthesized via the nitration of 2-methylpyridine using a mixture of nitric and sulfuric acids. The reaction requires careful control of temperature and stoichiometry to achieve high yields and selectivity. Palladium catalysts are sometimes used to improve the reaction outcome.

2-Methyl-4-nitropyridine is utilized in the pharmaceutical industry as an intermediate in drug synthesis. It also finds applications in the production of dyes, pigments, and as a component in certain sensing technologies and semiconductor manufacturing processes.

When handling 2-Methyl-4-nitropyridine, it is essential to use personal protective equipment (PPE) including gloves and safety goggles. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation. Spills should be contained and properly disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.