N-[(Benzyloxy)carbonyl]-D-alanine(CAS: 26607-51-2)

N-[(Benzyloxy)carbonyl]-D-alanine is a white to off-white crystalline solid with a molecular weight of approximately 260.27 g/mol. It is sparingly soluble in water and ethanol. The compound exhibits good reactivity, particularly in esterification and amidation reactions. Its solubility and reactivity make it suitable for various applications in organic synthesis and pharmaceuticals.

N-[(Benzyloxy)carbonyl]-D-alanine is typically synthesized through the reaction of D-alanine with benzyloxycarbonyl chloride in the presence of a base such as triethylamine. The process yields high selectivity and good to excellent yield, making it a common method in peptide and medicinal chemistry.

N-[(Benzyloxy)carbonyl]-D-alanine is used in the pharmaceutical industry for the synthesis of various drugs, particularly in peptide and amide-based compounds. It is also utilized in the polymer industry for the modification of polymers and in the semiconductor industry for the preparation of functional materials and sensors.

When handling N-[(Benzyloxy)carbonyl]-D-alanine, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate chemical spill response procedures. Always consult the Safety Data Sheet (SDS) for detailed handling and exposure information.