(2E)-3-Amino-2-methylacrylaldehyde(CAS: 30989-81-2)

The (2E)-3-Amino-2-methylacrylaldehyde (CAS: 30989-81-2) is a colorless liquid with a pungent odor. It has a molecular weight of approximately 128.14 g/mol and a boiling point of 158°C. The compound is soluble in water and ethanol. It is reactive, particularly towards nucleophiles, and can undergo condensation, reduction, and addition reactions.

The (2E)-3-Amino-2-methylacrylaldehyde (CAS: 30989-81-2) can be synthesized through the reductive amination of (2E)-3-methylacrylaldehyde with ammonia. This process involves the use of a reducing agent such as sodium borohydride and a base like sodium hydroxide. The yield is typically around 85%, with good selectivity towards the E-isomer.

The (2E)-3-Amino-2-methylacrylaldehyde (CAS: 30989-81-2) is used in various industries. It is a key intermediate in the synthesis of pharmaceuticals, particularly for the preparation of amino acids and other biologically active compounds. It is also used in the production of polymers, as a component in sensor systems, and in the development of semiconductors.

When handling (2E)-3-Amino-2-methylacrylaldehyde (CAS: 30989-81-2), it is essential to wear appropriate personal protective equipment (PPE), including gloves, protective goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation of fumes. Spills should be handled by neutralizing with an appropriate acid or base before cleanup. Always consult a Safety Data Sheet (SDS) for detailed handling and disposal instructions.