1-Bromo-2-(diethoxymethyl)benzene(CAS: 35822-58-3)

1-Bromo-2-(diethoxymethyl)benzene is a crystalline solid with a molecular weight of approximately 268.28 g/mol. It has a low water solubility and is moderately soluble in organic solvents like ethanol and acetone. It is less reactive compared to other brominated compounds but can undergo electrophilic aromatic substitution. It has a melting point of 63-65°C and a boiling point of 208-210°C under reduced pressure.

1-Bromo-2-(diethoxymethyl)benzene is typically synthesized via bromination of 2-(diethoxymethyl)benzene using a brominating agent such as N-bromosuccinimide (NBS) in the presence of a radical initiator like benzoyl peroxide. The reaction is carried out under mild conditions, providing good yield and selectivity. The product can be purified by recrystallization from suitable solvents.

1-Bromo-2-(diethoxymethyl)benzene is used in a variety of industries, including pharmaceuticals for synthesis of certain intermediates, and as a precursor in the production of polymers and sensors. Its use in semiconductors is less common but it can serve as a substrate for various functional groups in organic electronics.

When handling 1-Bromo-2-(diethoxymethyl)benzene, it is important to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a cool, dry place away from heat sources. Use a fume hood during handling to minimize inhalation of vapors. In case of spills, contain them with appropriate absorbent materials and follow your company's safety data sheet (SDS) guidelines for disposal. Always consult the latest SDS for specific safety information.