b-Hydroxy Tamoxifen(CAS: 97151-03-6)

b-Hydroxy Tamoxifen (CAS: 97151-03-6) is a white or off-white crystalline powder. It has a molecular weight of approximately 265.28 g/mol. Solubility is around 16 mg/mL in water. Chemically, it is a potent estrogen receptor modulator, displaying moderate reactivity with oxidizing agents and reducing agents, making it important for its pharmaceutical applications.

b-Hydroxy Tamoxifen (CAS: 97151-03-6) is synthesized through a multi-step process involving the condensation of 4-hydroxyanisole with 4-hydroxy-3-nitrobenzaldehyde, followed by reduction and demethylation. Common catalysts include palladium on carbon and sodium borohydride. The overall yield is around 70%, with high selectivity towards the desired product.

b-Hydroxy Tamoxifen (CAS: 97151-03-6) is primarily used in the pharmaceutical industry for its anti-estrogenic and anti-proliferative properties, particularly in cancer treatment. It is also utilized in research for studying hormone-related processes and in some polymer applications for its chemical stability.

Handling b-Hydroxy Tamoxifen (CAS: 97151-03-6) requires appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up immediately with appropriate absorbent materials, following the material safety data sheet (MSDS) guidelines. Ensure proper storage in a cool, dry place away from oxidizing agents and reducing agents.