Cabozantinib s-malate(CAS: 1140909-48-3)

Cabozantinib s-malate is a prodrug of cabozantinib, which is a multikinase inhibitor used in the treatment of various cancers. It is composed of cabozantinib and s-malate, a derivative of malic acid, which enhances the drug's stability and bioavailability.

Cabozantinib s-malate is primarily used in the treatment of medullary thyroid cancer (MTC) and renal cell carcinoma (RCC) after failure of prior therapy. It targets multiple kinases involved in tumor growth and progression, making it effective in cancer therapy.

Cabozantinib s-malate is generally safe when used as directed. However, it can cause side effects such as hypertension, hand-foot syndrome, and fatigue. Patients should consult a healthcare provider for proper dosage and monitoring to minimize risks. Storage and handling should follow safety guidelines to prevent exposure and inhalation.

Cabozantinib s-malate should be stored at room temperature (15-30°C) away from direct sunlight and moisture. It should be kept in a tightly closed container to protect against light and air. Avoid storing in high humidity areas to maintain stability and efficacy. Proper disposal should be followed to prevent environmental contamination.