5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline(CAS: 863578-21-6)

5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is a crystalline solid with a molecular weight of approximately 368.03 g/mol. It has a low solubility in water but good solubility in organic solvents. The compound is relatively stable but can undergo substitution reactions. It is typically used in organic synthesis and as a precursor in the development of new materials.

5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is commonly synthesized through a multistep process involving the coupling of aniline with dichloroborane in the presence of a base such as potassium carbonate. The reaction is typically carried out in an inert solvent like dimethylformamide (DMF). The process yields a high percentage of the desired product with good selectivity.

5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is primarily used in the pharmaceutical and polymer industries. It serves as a key intermediate in the synthesis of various drugs and is also utilized in the production of novel polymers with enhanced properties.

When handling 5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline, it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and flammable materials. In case of a spill, neutralize with an appropriate base and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.