4,4,4-Trifluoro-1-butanol(CAS: 461-18-7)

4,4,4-Trifluoro-1-butanol is a colorless liquid with a molecular weight of 150.08 g/mol. It has a low solubility in water (0.1 g/100 mL at 20°C) and is more soluble in organic solvents. It is relatively stable under normal conditions but can react with strong bases. It is used in the synthesis of other compounds and as a reagent in organic chemistry.

4,4,4-Trifluoro-1-butanol is typically synthesized via the reaction of 1-bromobutane with hydrogen fluoride to form 4-bromofluorobutane, which is then reduced to 4,4,4-trifluoro-1-butanol using sodium borohydride or lithium aluminum hydride. The reaction is carried out under anhydrous conditions to promote the desired product formation.

4,4,4-Trifluoro-1-butanol is used in various industries, including pharmaceuticals, where it serves as a starting material for the synthesis of other compounds. It is also used in the polymer industry for the production of certain plastics and in the manufacturing of sensors and semiconductors for electronic applications.

When handling 4,4,4-trifluoro-1-butanol, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. The substance should be handled in a well-ventilated area or under a fume hood due to its volatility. Spills should be cleaned up with appropriate absorbents, and the area should be flushed with water. Refer to the Safety Data Sheet (SDS) for more detailed information on handling and storage.