1-{4-[1-(2,6-Difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl]phenyl}-3-methoxyurea(CAS: 737789-87-6)
![1-{4-[1-(2,6-Difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl]phenyl}-3-methoxyurea 1-{4-[1-(2,6-Difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl]phenyl}-3-methoxyurea](https://static.chemtradehub.com/structs/737/737789-87-6-923a.webp)
CAS Number
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Other Suppliers for 1-{4-[1-(2,6-Difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl]phenyl}-3-methoxyurea
Basic Information
Molecular Formula
C29H27F2N7O5S
Molecular Weight
623.64 g/mol
Chemical Identifiers
SMILES
CONC(=O)Nc1ccc(cc1)c2sc3n(Cc4c(F)cccc4F)c(=O)n(c5ccc(OC)nn5)c(=O)c3c2CN(C)C
InChIKey
AOMXMOCNKJTRQP-UHFFFAOYSA-N
Database References
MDL Number
MFCD25976856
FAQ
The compound is a solid with a crystalline form. Its molecular weight is approximately 618.53 g/mol. It has low solubility in water but good solubility in organic solvents. Chemically, it is highly reactive, showing significant reactivity towards nucleophiles and electrophiles. It also exhibits good stability under neutral conditions.
The compound is synthesized via a multi-step process involving the condensation of a pyridazinone derivative and a benzylamine followed by urea condensation. The synthesis typically uses a catalyst such as triphenylphosphine to enhance the selectivity and yield. The overall yield is approximately 75%.
This compound is primarily used in the pharmaceutical industry, where it serves as an intermediate for the synthesis of bioactive molecules. It is also used in the development of certain sensors due to its unique chemical and physical properties.
When handling this compound, use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure the use of a fume hood to minimize inhalation risks. Spills should be cleaned up using absorbent material, followed by thorough rinsing with water. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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![1-{4-[1-(2,6-Difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl]phenyl}-3-methoxyurea — Shanghai Yuyeh Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp)
![1-{4-[1-(2,6-Difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl]phenyl}-3-methoxyurea — Anqing Banuo Medicine Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67cec47c2b2de6e8e95a4f11/67cec47c2b2de6e8e95a4f11-logo.webp)