N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-leucine(CAS: 16937-99-8)

N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-leucine (CAS: 16937-99-8) is a crystalline compound with a molecular weight of approximately 260.41 g/mol. It has a melting point of 158-160°C and is slightly soluble in water. The compound is stable under normal conditions, but it can react with strong bases to form amides. It is also susceptible to hydrolysis in aqueous solutions.

N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-leucine (CAS: 16937-99-8) is typically synthesized through a multi-step reaction involving carbonylation of D-leucine followed by esterification. Commonly, this compound is produced using a catalytic system with palladium or rhodium catalysts. The yield is usually around 70-80%, with good selectivity for the desired product.

N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-leucine (CAS: 16937-99-8) is used in various industries. In pharmaceuticals, it serves as a precursor for synthesizing other peptides and peptidomimetics. It is also utilized in the polymer industry for the preparation of biodegradable polymers. Additionally, this compound has potential applications in the sensor and semiconductor industries due to its structural properties.

When handling N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-leucine (CAS: 16937-99-8), it is crucial to follow appropriate safety measures. Wear appropriate personal protective equipment (PPE), including gloves and safety glasses. Store the compound in a cool, dry place away from strong acids and bases. In case of a spill, immediately contain it and clean up with appropriate materials. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.