Methyl 1-methyl-3-piperidinecarboxylate(CAS: 1690-72-8)

Methyl 1-methyl-3-piperidinecarboxylate (CAS: 1690-72-8) is a colorless liquid with a molecular weight of approximately 141.18 g/mol. It has a pKa of around 12.5, indicating basic properties. The compound is soluble in organic solvents such as ethanol and acetone. It is slightly soluble in water. It is relatively stable under normal conditions but can react with strong acids to form carboxylic acid derivatives.

Methyl 1-methyl-3-piperidinecarboxylate (CAS: 1690-72-8) can be synthesized via the condensation of methyl acetoacetate with 1-methylpiperazine. Commonly, the reaction is carried out in the presence of a base like sodium hydroxide or potassium carbonate. The yield and selectivity of this method are good, making it a practical and industrially relevant approach.

Methyl 1-methyl-3-piperidinecarboxylate (CAS: 1690-72-8) is primarily used in pharmaceuticals for the synthesis of various drugs. It also finds applications in polymer production, as a monomer or additive. Additionally, it can be used in the manufacturing of sensors and semiconductors due to its unique chemical properties.

When handling Methyl 1-methyl-3-piperidinecarboxylate (CAS: 1690-72-8), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. Fume hoods should be used during handling to minimize inhalation risks. In case of spill, it should be cleaned up carefully following standard laboratory safety protocols. Safety Data Sheets (SDS) should be consulted for detailed information on handling and storage.