2-Bromo-1,3-thiazole(CAS: 3034-53-5)

2-Bromo-1,3-thiazole (CAS: 3034-53-5) is a crystalline solid with a molecular weight of 165.01 g/mol. It has a low solubility in water (0.05 g/100 mL at 20°C) and exhibits good solubility in organic solvents like acetone and dimethyl sulfoxide. This compound is known for its high reactivity towards nucleophiles, particularly in the presence of amines and thiols.

2-Bromo-1,3-thiazole (CAS: 3034-53-5) is typically synthesized through the bromination of 1,3-thiazole using N-bromosuccinimide (NBS) in the presence of a suitable initiator such as benzoyl peroxide. The reaction is carried out under anhydrous conditions to enhance selectivity and yield.

2-Bromo-1,3-thiazole (CAS: 3034-53-5) finds applications in various industries, including pharmaceuticals, where it serves as a precursor for synthesizing medicinal compounds; polymers, where it can be used as a stabilizer; sensors, where its reactivity can be utilized for detection purposes; and semiconductors, where its properties can contribute to the development of advanced materials.

When handling 2-Bromo-1,3-thiazole (CAS: 3034-53-5), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. This compound should be used in a well-ventilated area or a fume hood to minimize inhalation risks. Proper spill handling procedures should be followed, and safety data sheets (SDS) should be consulted for detailed information on safe handling practices.