Ethyl 5-chloropyrazolo[1,5-a]pyrimidine-3-carboxylate(CAS: 1224944-77-7)

Ethyl 5-chloropyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS: 1224944-77-7) is a white crystalline solid with a molecular weight of 241.57 g/mol. It is soluble in polar solvents such as methanol and acetone but has low solubility in water. This compound is known for its high reactivity, particularly in nucleophilic substitution reactions.

Ethyl 5-chloropyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS: 1224944-77-7) is synthesized through a multi-step process involving the condensation of 5-chloropyrazole and ethyl cyanoacetate, followed by hydrolysis. The reaction is catalyzed by a combination of acid and base, with high selectivity and a yield of approximately 85%.

Ethyl 5-chloropyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS: 1224944-77-7) is used in the pharmaceutical industry for the development of new drugs, as well as in the production of sensors and semiconductors. Its unique functional groups make it suitable for various applications requiring specific chemical properties.

When handling Ethyl 5-chloropyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS: 1224944-77-7), it is important to use personal protective equipment (PPE) such as gloves and goggles. Storage should be in a cool, dry place away from direct sunlight. In case of spill, use appropriate absorption materials and consult the Material Safety Data Sheet (MSDS) for further instructions. Ensure proper ventilation in the laboratory and work within a fume hood.