Methyl 4-piperidinylacetate hydrochloride (1:1)(CAS: 81270-37-3)

Methyl 4-piperidinylacetate hydrochloride is a crystalline compound with a molecular weight of approximately 199.7 g/mol. It has a low solubility in water but is soluble in organic solvents. The compound is mildly basic and can react with acidic compounds. It is stable under normal storage conditions but should be kept away from strong oxidizing agents.

Methyl 4-piperidinylacetate hydrochloride is typically synthesized by reacting piperidine with acetyl chloride in the presence of a suitable base like sodium bicarbonate. The reaction is conducted at room temperature and yields a mixture that is then hydrolyzed with hydrochloric acid to form the hydrochloride salt. The product is isolated by crystallization.

Methyl 4-piperidinylacetate hydrochloride finds applications in pharmaceuticals, particularly as an intermediate for the synthesis of certain drugs. It is also used in the synthesis of polymers and as a precursor in the development of sensors and semiconductors.

When handling Methyl 4-piperidinylacetate hydrochloride, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or under a fume hood. Spills should be cleaned up using appropriate absorbents, and the area should be properly ventilated. Always consult the Safety Data Sheet (SDS) for detailed safety information.