8-Chloro-11-(4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-5-ol(CAS: 117811-12-8)

8-Chloro-11-(4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-5-ol is a yellow to orange solid with a molecular weight of approximately 293.8 g/mol. It has a low solubility in water but is soluble in organic solvents like DMSO. This compound is highly reactive, particularly towards nucleophiles and electrophiles, and can be used in various synthetic transformations.

8-Chloro-11-(4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-5-ol can be synthesized via a multistep process involving the condensation of 4-piperidone with 8-chloro-11-formyl-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-5-one. This reaction is catalyzed by Lewis acids such as aluminum chloride or zinc chloride, leading to high selectivity and good yield.

8-Chloro-11-(4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-5-ol is used in pharmaceuticals for the development of certain bioactive compounds and in the semiconductor industry for electronic applications due to its unique structural features.

When handling 8-Chloro-11-(4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-5-ol, use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store in a well-ventilated area and use a fume hood during manipulations. In case of spill, clean up with appropriate absorbents and follow standard safety protocols. Refer to the Material Safety Data Sheet (MSDS/SDS) for detailed handling guidelines.