N'-(5-Bromo-2-pyridinyl)-N,N-dimethylimidoformamide(CAS: 138888-98-9)

N'-(5-Bromo-2-pyridinyl)-N,N-dimethylimidoformamide (CAS: 138888-98-9) is a crystalline solid with a molecular weight of approximately 292.04 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and acetonitrile. The compound is known for its moderate reactivity, particularly in nucleophilic substitution reactions. It is stable under normal laboratory conditions but should be stored in a dry, cool place away from direct sunlight.

N'-(5-Bromo-2-pyridinyl)-N,N-dimethylimidoformamide (CAS: 138888-98-9) can be synthesized via a multi-step process involving the bromination of 2-pyridinecarboxaldehyde followed by a condensation reaction with dimethylformamide. The reaction typically requires a catalyst such as an acid to ensure selectivity, and the yield is moderate, around 70-80%. The final product is isolated by recrystallization from an appropriate solvent.

N'-(5-Bromo-2-pyridinyl)-N,N-dimethylimidoformamide (CAS: 138888-98-9) finds applications in various industries, particularly in the pharmaceutical sector for its use as an intermediate in the synthesis of medicinal compounds. It is also utilized in the development of sensors and semiconductors due to its unique chemical properties.

When handling N'-(5-Bromo-2-pyridinyl)-N,N-dimethylimidoformamide (CAS: 138888-98-9), it is essential to follow proper laboratory safety protocols. Wear appropriate personal protective equipment (PPE), including gloves and safety goggles, and handle the compound in a well-ventilated fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbents, and proper disposal of waste should follow local regulations. Always refer to the safety data sheet (SDS) for detailed handling and storage instructions.