Tenofovir Impurity 122 (Isopentenyl-Adenine)(CAS: 2365-40-4)

Tenofovir Impurity 122, also known as Isopentenyl-Adenine, is a nucleoside analog with the chemical formula C10H13N5O4P. It is a white crystalline powder, highly soluble in water, and commonly used as an impurity in the synthesis of tenofovir. Its structure resembles adenosine but features an isopentenyl group instead of a ribose sugar, making it relevant in pharmaceutical research and drug purity analysis.

Tenofovir Impurity 122 (Isopentenyl-Adenine) is primarily used in pharmaceutical research to study impurity profiles during the production of antiretroviral drugs like tenofovir. It also serves as a precursor in the synthesis of nucleoside analogs and is employed in analytical chemistry for quality control in drug manufacturing. Additionally, it is relevant in biochemical studies related to nucleotide metabolism and enzyme activity.

Tenofovir Impurity 122 (Isopentenyl-Adenine) is not intended for human or animal use and should be handled with care in laboratory settings. While specific toxicity data may be limited, standard safety precautions include wearing gloves, goggles, and ensuring adequate ventilation. It is classified under controlled chemical handling protocols, and safety standards emphasize avoiding exposure through proper containment and disposal practices.

Tenofovir Impurity 122 (Isopentenyl-Adenine) should be stored in a cool, dry, and dark place, ideally at 2-8°C, to maintain stability. It requires airtight containers to prevent moisture absorption and degradation. Avoid exposure to light and humidity, and ensure storage in a well-ventilated area. Keep away from incompatible substances and follow proper labeling for safe handling.