N-(1,3-Benzodioxol-5-ylmethyl)-4-([1]benzofuro[3,2-d]pyrimidin-4-yl)-1-piperazinecarbothioamide(CAS: 850879-09-3)

N-(1,3-Benzodioxol-5-ylmethyl)-4-([1]benzofuro[3,2-d]pyrimidin-4-yl)-1-piperazinecarbothioamide is a crystalline compound with a molecular weight of approximately 538.5 g/mol. It has a solubility of 1-2 g/L in water and is poorly soluble in organic solvents. The compound is less reactive under normal conditions but can undergo hydrolysis under basic conditions. It has a melting point of 190-192°C and is stable under normal storage conditions.

N-(1,3-Benzodioxol-5-ylmethyl)-4-([1]benzofuro[3,2-d]pyrimidin-4-yl)-1-piperazinecarbothioamide is synthesized via multistep reactions. The key steps involve the preparation of benzodioxol derivative, followed by coupling with piperazinecarbothioamide. The synthesis typically employs catalytic amounts of a suitable coupling agent and proceeds with good yield (70-80%).

N-(1,3-Benzodioxol-5-ylmethyl)-4-([1]benzofuro[3,2-d]pyrimidin-4-yl)-1-piperazinecarbothioamide is primarily used in the pharmaceutical industry for its potential as a therapeutic agent. It may also find applications in the development of sensors and semiconductors due to its unique chemical properties.

When handling N-(1,3-Benzodioxol-5-ylmethyl)-4-([1]benzofuro[3,2-d]pyrimidin-4-yl)-1-piperazinecarbothioamide, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.