6-Amino-1-methyl-5-nitroso-2,4(1H,3H)-pyrimidinedione(CAS: 6972-78-7)

6-Amino-1-methyl-5-nitroso-2,4(1H,3H)-pyrimidinedione is a white or off-white crystalline solid with a molecular weight of approximately 232.13 g/mol. It is slightly soluble in water and organic solvents like ethanol and acetone. This compound shows moderate reactivity, particularly towards nucleophiles and reducing agents.

6-Amino-1-methyl-5-nitroso-2,4(1H,3H)-pyrimidinedione is synthesized from 1-methyl-5-nitropyrimidine-2,4-dione through amination reaction. Commonly, this involves treating the nitroso compound with an amine, such as methylamine, in the presence of a base like sodium hydroxide. The conditions include refluxing under an inert atmosphere to ensure the reaction goes to completion.

6-Amino-1-methyl-5-nitroso-2,4(1H,3H)-pyrimidinedione is used in the pharmaceutical industry for the synthesis of various organic compounds and in the development of new drugs. It also finds applications in the polymer industry as a stabilizer and in the production of sensors and semiconductors for electronic devices.

When handling 6-Amino-1-methyl-5-nitroso-2,4(1H,3H)-pyrimidinedione, it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be carried out in a fume hood to avoid inhalation. In case of a spill, immediately clean the area with water and dispose of the waste according to local regulations. Always refer to the safety data sheet (SDS) for detailed information on handling and storage.