2-Bromo-3-methylthiophene(CAS: 14282-76-9)

2-Bromo-3-methylthiophene (CAS: 14282-76-9) is a colorless liquid with a molecular weight of approximately 167.02 g/mol. It has a boiling point of 183-185°C and a melting point of -24°C. The compound is moderately soluble in water but highly soluble in organic solvents. It is chemically reactive towards nucleophiles and can undergo substitution reactions.

2-Bromo-3-methylthiophene (CAS: 14282-76-9) is commonly synthesized via the bromination of 3-methylthiophene using N-bromosuccinimide (NBS) in the presence of a peroxide initiator such as benzoyl peroxide. The reaction is typically carried out in an inert solvent like dichloromethane under reflux conditions, achieving good yield and selectivity.

2-Bromo-3-methylthiophene (CAS: 14282-76-9) is used in the pharmaceutical industry for the synthesis of certain intermediates and drug candidates. It also finds applications in the semiconductor industry as a precursor for organic semiconductors. Additionally, it is utilized in the polymer industry for the development of conductive polymers and in the sensor industry for gas sensing applications.

Proper handling of 2-Bromo-3-methylthiophene (CAS: 14282-76-9) requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from heat and oxidizing agents. In case of a spill, it should be contained and neutralized using appropriate absorbents. Always refer to the safety data sheet (SDS) for detailed handling and disposal information.