4-(Trimethylsilyl)benzaldehyde(CAS: 2199-32-8)

4-(Trimethylsilyl)benzaldehyde is a crystalline compound with a molecular weight of approximately 226.38 g/mol. It has a melting point of 58-59°C and is poorly soluble in water but soluble in common organic solvents. Chemically, it is relatively stable but can react with strong bases and acids. It is used as a precursor in organic synthesis and as a reagent in various chemical reactions.

4-(Trimethylsilyl)benzaldehyde is typically synthesized through the reaction of benzaldehyde with trimethylsilyl chloride in the presence of a base like sodium hydride. The reaction proceeds with good regioselectivity and yields a high percentage of the desired product. The process is optimized for high selectivity and yield.

4-(Trimethylsilyl)benzaldehyde is utilized in the pharmaceutical and polymer industries. It serves as a key intermediate in the synthesis of various drugs and polymers. Additionally, it is used in the production of chelating agents and as a reagent in organic synthesis for the development of new materials and pharmaceuticals.

When handling 4-(Trimethylsilyl)benzaldehyde, ensure proper ventilation and use in a fume hood. Wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Store the compound in a well-ventilated and dry area away from heat sources. In case of a spill, handle it carefully and follow proper waste disposal procedures. Refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.