4-Nitro-1H-pyrazole(CAS: 2075-46-9)

4-Nitro-1H-pyrazole (CAS: 2075-46-9) is a white crystalline solid with a molecular weight of 145.05 g/mol. It has a melting point of 259-260°C and is slightly soluble in water. This compound shows good stability under normal conditions but can be reactive in the presence of strong acids or bases. It is used in various chemical reactions due to its electronic properties.

4-Nitro-1H-pyrazole (CAS: 2075-46-9) is commonly synthesized via the nitration of 1H-pyrazole. This process involves the reaction of 1H-pyrazole with nitric acid in the presence of a suitable catalyst, such as sulfuric acid. The yield is usually around 80-85%, and the product is isolated by recrystallization from aqueous solvent.

4-Nitro-1H-pyrazole (CAS: 2075-46-9) is utilized in pharmaceuticals for the synthesis of certain drug intermediates. It also finds applications in the development of sensors, semiconductors, and polymers due to its unique electronic properties. Its use in these industries leverages its stability and reactivity under various conditions.

When handling 4-Nitro-1H-pyrazole (CAS: 2075-46-9), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be immediately cleaned up with appropriate absorbents, and the area should be flushed with water. Refer to the Safety Data Sheet (SDS) for detailed information on handling and storage procedures.