Methyl 4-methylbenzenesulfonate(CAS: 80-48-8)

Methyl 4-methylbenzenesulfonate, also known as methyl p-toluenesulfonate, is an organic sulfonate compound with the chemical formula C8H10O3S. It is a colorless liquid with a sharp odor, soluble in organic solvents, and commonly used as a methylating agent due to its ability to transfer methyl groups in chemical reactions. Its structure features a sulfonic acid group attached to a methyl-substituted benzene ring.

Methyl 4-methylbenzenesulfonate is primarily used in pharmaceuticals for synthesizing complex organic molecules, in industrial applications as a solvent or catalyst, and in research for acetylation and esterification reactions. It serves as a key reagent in organic chemistry for introducing methyl groups into aromatic compounds, making it valuable in drug development and chemical manufacturing processes.

Methyl 4-methylbenzenesulfonate is considered toxic and requires careful handling. Safety measures include wearing protective gloves, goggles, and lab coats, and ensuring proper ventilation. It is classified as a hazardous substance under OSHA and EPA guidelines, so adherence to safety protocols and avoidance of direct contact or inhalation is essential to minimize health and environmental risks.

Methyl 4-methylbenzenesulfonate should be stored in a cool, dry, and dark place, preferably in a sealed container made of glass or HDPE. It is stable under normal conditions but must be protected from moisture and heat. Storage areas should be well-ventilated, and the compound should be kept away from incompatible materials to maintain its integrity and safety.