Methyl 5-bromo-6-chloronicotinate(CAS: 78686-77-8)

Methyl 5-bromo-6-chloronicotinate is a bromo- and chloro-substituted nicotinate derivative with the chemical formula C8H7BrClNO2. It is a white crystalline solid, commonly used as a chemical intermediate in pharmaceutical and organic synthesis applications. The compound exhibits moderate solubility in polar solvents and is characterized by its aromatic pyridine ring with functional groups, making it valuable in drug development. Its unique structure allows for tailored reactivity in various chemical reactions, supporting its role in synthetic chemistry.

Methyl 5-bromo-6-chloronicotinate is primarily used in pharmaceutical research for synthesizing antidiabetic, anti-inflammatory, and antiviral compounds. It also serves industrial purposes, such as in dye and pesticide production, due to its reactivity. In research settings, it functions as a building block for creating novel organic molecules. Additionally, it may be utilized in food additives or as a precursor for other chemical derivatives, depending on the application.

Methyl 5-bromo-6-chloronicotinate is considered hazardous and requires careful handling. It may cause respiratory or skin irritation and is toxic if ingested or inhaled. Safety standards include following OSHA and EPA guidelines, using appropriate PPE like gloves and goggles, and ensuring proper ventilation. It is classified under GHS as a substance requiring caution in industrial and laboratory environments.

Store Methyl 5-bromo-6-chloronicotinate in a cool (2-8°C), dry, and dark location in sealed, airtight containers to prevent moisture and light exposure. Avoid contact with incompatible materials and ensure proper ventilation. Maintain stability by keeping it away from air and heat sources, and follow specific safety protocols for chemical storage to minimize risks.