2-(1-Cyclohexen-1-yl)ethanamine(CAS: 3399-73-3)

2-(1-Cyclohexen-1-yl)ethanamine is a colorless to pale yellow liquid with a molecular weight of approximately 134.24 g/mol. It has a solubility of about 12.6 g/100 mL in water at 25°C. Chemically, it shows basic properties due to the amine group. It reacts with acids to form salts and can undergo nucleophilic substitution reactions.

2-(1-Cyclohexen-1-yl)ethanamine is typically synthesized via alkylation of cyclohexanone with ethylamine. The reaction usually proceeds through a Grignard reagent formed from cyclohexanone and magnesium, followed by the addition of ethylamine. The process yields the desired compound with good selectivity and moderate to high yield.

2-(1-Cyclohexen-1-yl)ethanamine finds applications in the pharmaceutical industry for the synthesis of certain drugs, as well as in the polymer industry for the production of functionalized polymers. It is also used in the development of sensors and semiconductors for its electronic and chemical properties.

When handling 2-(1-Cyclohexen-1-yl)ethanamine, it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be handled carefully using appropriate absorbent materials and cleaned up immediately. Always refer to the Material Safety Data Sheet (MSDS/SDS) for additional safety information.